Product Overview
IGF-1 LR3 is a long-acting analog of Insulin-like Growth Factor-1 designed for investigating anabolic signaling, muscle cell proliferation, hypertrophy pathways, and tissue repair mechanisms in preclinical models. This modified peptide features an extended arginine chain at the N-terminus and a substitution at position 3, resulting in significantly prolonged half-life and reduced binding to IGF-binding proteins compared to native IGF-1, allowing sustained receptor activation. It is commonly studied for its potential to stimulate satellite cell activation, protein synthesis via PI3K/Akt and MAPK pathways, and regenerative processes in muscle, cartilage, and other tissues under experimental conditions such as injury, catabolic states, or growth factor deficiency models. It is supplied as high-purity lyophilized powder in sealed sterile vials for reliable reconstitution and lab results.
Key Features
- Anabolic and Regenerative Mechanisms: IGF-1 LR3 directly activates IGF-1 receptors to promote muscle cell hyperplasia and hypertrophy, enhance protein synthesis, and support satellite cell proliferation and differentiation in preclinical tissue growth and repair models.
- High Purity: Each batch is rigorously tested for purity (>99%) and sterility via HPLC and mass spectrometry, ensuring consistent and reliable research outcomes.
- Lyophilized Powder: Provided in sealed, sterile vials for easy reconstitution, stability, and long-term storage.
- Research-Grade: Formulated specifically for in-vitro and pre-clinical studies, not for human or animal use.
Research Applications
BIOCLINX IGF-1 LR3 1mg is a novel peptide under investigation for its potential in:
- Muscle Hypertrophy and Growth Pathways: Exploring satellite cell activation, fiber proliferation, and protein synthesis in experimental models of muscle development or resistance training simulations.
- Tissue Repair and Regeneration: Investigating accelerated healing and structural recovery in muscle, tendon, and cartilage injury or damage models through enhanced cellular proliferation and matrix support.
- Countering Catabolic States: Probing protective effects on lean mass preservation and recovery in catabolic, fasting, or glucocorticoid-exposed preclinical settings.
- Metabolic and Cellular Signaling: Highlighting sustained IGF-1 receptor activation for insights into glucose uptake, mitochondrial function, and broader anabolic physiology versus native IGF-1 in laboratory studies.
Product Specifications
- Form: Lyophilized powder in sterile glass vials
- Molecular Weight: Approximately 9117 Da
- CAS Number: 946870-92-4
- Available Sizes: 1 mg vial
- Storage: Store at -20°C, protected from light and moisture
Why Choose Our IGF-1 LR3 1mg?
- Trusted Quality: Every batch undergoes mass spectrometry and HPLC testing for purity.
- Fast Shipping: Secure, Fast, and FREE 2-Day Shipping
- Research Support: Access detailed product documentation and Certificates of Analysis upon request.
Disclaimer
This product is sold strictly for scientific research purposes only. It is not intended for diagnosis, treatment, or prevention of any disease. Handle only by licensed professionals with appropriate equipment and facilities. By purchasing, you agree to assume all risks associated with handling and use.